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Muscular pain also does not cause numbness, tingling, or electric based pain
NAPQI can be detoxified by subsequent phase II metabolism via conjugation with glutathione (GSH), partly mediated by different glutathione S -transferase (GST) isozymes (Figure 1) (Mitchell et al., 1973b)
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Later meta-analyses also report small but significant reductions in body weight, BMI or fat mass, with effects more relevant in overweight or obese populations
When activated, microglia release inflammatory chemicals that amplify pain signaling and contribute to: Widespread pain Nerve pain Brain fog Fatigue Sleep disruption Increased pain sensitivity This is one reason pain may persist even after an injury has structurally healed
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