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Grant, et al
Kumar says that more research is needed to understand what drives these effects, and GLP-1s are not currently FDA-approved to treat addiction disorders
By keeping the structure so close to the native hormone, the researchers aimed to create a compound that would preferentially bind to the primary target, the MC1R, with minimal spillover to other receptors
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Glucagon Receptor: Historically known for raising blood sugar, activating this receptor in the specific context of Retatrutide appears to increase energy expenditure and promote direct fat burning in the liver
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