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The incidence of affected segments was relatively higher for the ascending colon and transverse colon and lower for the sigmoid colon and rectum in both men and women

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Weiner suggests that in many cases, medications like GLP-1s may offer better outcomes than revision surgeries

Furthermore, TMAO can downregulate intestinal tight junction protein expression, increasing intestinal permeability and establishing a vicious cycle of gut leakage and renal injury (173)

Martinez-Hernandez A, Bell KP, Norenberg MD