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The 32-week, multicentre, randomized, double-blind, active-controlled phase 2 trial aimed to evaluate the efficacy and safety of the combination therapy
Its mechanism aligns well with a long-term skin-maintenance approach
An elevated methylmalonic acid (MMA) level has been thought to be the most direct, metabolic indicator of B12 deficiency because B12 is the only cofactor required by the enzyme that degrades MMA
To evaluate the cell migration, a transwell assay was conducted
The peptide's ability to promote tendon fibroblast migration, enhance collagen synthesis, and support vascular ingrowth addresses key biological requirements for tendon repair
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