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It should be avoided with active cancer, and it is not used during pregnancy or breastfeeding

To address this, we studied glutamate and glutathione metabolism enzymes in blood cells in 53 older adult patients with depression and 20 controls

As regards the fibrinolytic process, an impairment of the binding and action of tissue-type plasminogen activator (t-PA) at the endothelial cell surface has been reported in the presence of homocysteine, which would thus inhibit endothelial-dependent fibrinolysis (Hajjar, 1993)

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