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In this issue of Pediatric Research , Romariz et al

In addition, SIRT1 can also deacetylate the AMPK upstream kinase LBK1 and activate AMPK 42

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PLoS ONE (2018) 13:e0192441

This may lead to some overestimation of the eligible population of patients without diabetes, though the overweight/obese population of patients without diabetes remains substantial regardless