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Novo Nordisk holds semaglutide composition-of-matter and formulation patents expiring between 2031 and 2038 across different jurisdictions, with FlexTouch autoinjector device patents extending GLP-1 competitive protection in the U.S
In fact, many plaintiffs allege that pharmaceutical companies improperly marketed the weight loss drug for off-label use without adequately warning patients about serious adverse effects
They indicate that identity, manufacture, impurity control, aggregation, formulation, route, and exposure cannot be assumed safe from the peptide name or an HPLC purity value alone
Procedures such as sleeve gastrectomy and Roux-en-Y gastric bypass produce average weight reductions of 25 to 35% and remain the most durable interventions available for severe obesity and obesity-related metabolic disease
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