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Pigmentation that has not improved with creams or home remedies : Deeper discoloration usually needs medical intervention to fade safely

How Do Tirzepatide Weight Loss Injections Work

Patients who switched from tirzepatide to orforglipron maintained a mean 74.7% of their body weight reduction from the SURMOUNT-5 trial compared with those in the placebo group, which maintained a mean 49.2% of their weight loss

This implies that GLP-1RAs may support BMD maintenance during weight loss, providing a dual advantage in the management of diabetes (67)

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