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Constipation, diarrhea, anatomy, motility, surgery, and malabsorption risk affect interpretation

metabolic changes during treatment reflect normal adaptation to weight loss rather than drug-induced harm

Data from a pivotal Phase I/II/III trial and long-term safety and efficacy study together showed the therapy could significantly lessen severe vaso-occlusive events and hospitalizations

Glutathione levels also decline naturally with age, which means life-long athletes and older active adults are working with a lower baseline before training load is even factored in

All patients aged 18 years, positive for hepatitis B surface antigen (HBsAg) and antibodies to HDV (anti-HD), were considered eligible