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Patients pushed to the maximum dose in 8 to 12 weeks lose more than patients titrated over the full 16-plus week schedule
The data now line up in a clean story: Phase 1 established dose response and feasibility Phase 2 showed high-magnitude weight loss over 48 weeks Phase 3 showed the effect can hold up in harder-to-treat groups That sequence is what makes retatrutide more than just a flashy trial result
The body can't really handle that much protein at once
Youre also not giving up a proven medication
