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Inflammation is a common underlying factor in many chronic health conditions
& Arndt, K
doi:10.1038/s41366-025-01859-6 51
MCH1R antagonists have also been shown to be efficacious in animal models of depressive behavior although the precise mechanism for the antidepressant effects are not yet clearly defined
However, cDC3s arise from a unique Ly6C+ monocyte-DC progenitor, as opposed to the common DC progenitor giving rise to cDC1/2s, and thus represent a divergent lineage
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