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Thompson et al., 2024a)

In this article we review the pharmacology and design of ADCs, as well as we describe the results of different studies evaluating ADCs in lung cancer directed to several targets including HER2, HER3, TROP2, MET, CEACAM5 and DLL3

In hepatocytes, SREBP2 activation increased HMGCR transcription, but ALC reverses this trend