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However the broad spectrum of changes that are induced by this group of drugs in immunometabolism, gut and gut microbiome biology, and the possible direct effect on mast cell degranulation should encourage further observations and studies in this field

The medication does not directly target sugar receptors but may reduce the rewarding sensation of high-sugar foods through effects on dopamine signalling

Tirzepatide is a dual-action medication that activates both GLP-1 and GIP receptors

Current Opinion in Supportive and Palliative Care, 9 (2), 189195

It is studied in preclinical models to investigate mitochondrial biogenesis enhancement, cellular energy metabolism regulation, neuronal metabolic support, and potential cognitive effects