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Scopolamine hydrobromide at a dose of 70 nmol was administered to induce memory deficits reminiscent of Alzheimers disease
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On each day of the 10-week treatment period, oral administration was performed in the morning after an overnight fast of 10 h (water was allowed until 2 h before dosing) followed by 2-h post-dose fasting where subjects were not allowed to take any other oral concomitant medications
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