This can be due to viral infections (like dengue, hepatitis C), vitamin deficiencies (B12, folate), aplastic anemia, or as a side effect of chemotherapy and radiation
For example, why do people with diabetes lose less weight than obese, non-diabetics (first Figure from this post expanded to show the difference for the various drugs)
High epidemiological reliability denotes the strongest available evidence with no indication of significant variance or bias ( (i) Persuasive: statistical significance per the random-effects model of p 1,000 cases, low heterogeneity among the selected studies ( I 2 1,000 cases, and most studies indicating a significant effect
Tesofensine is a serotonin-noradrenaline-dopamine reuptake inhibitor (SNDRI), a type of drug that influences the levels of neurotransmitters involved in mood, motivation, and appetite
Signs include dizziness, blurred vision, anxiety, sweating, slurred speech, shakiness, confusion, a fast heartbeat or feeling jittery