What Is MOTS c MOTS c is a mitochondrial derived peptide encoded by mitochondrial DNA
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Senescent cells are cells that have permanently halted their cell cycle ('replicative arrest') but resist apoptosissometimes called 'zombie cells.' They accumulate with age in multiple tissues and secrete a pro-inflammatory cocktail called the Senescence-Associated Secretory Phenotype (SASP), containing IL-6, IL-8, MMP-3, MMP-9, TNF-, and other factors that damage surrounding healthy tissue
The most frequently reported reactions include: Redness (erythema) at the application site Itching or a tingling/stinging sensation , especially on freshly exfoliated or compromised skin Dryness or mild flaking , sometimes related to the overall formulation rather than the peptide itself Temporary irritation when combined with strong actives These reactions typically resolve on their own or after reducing frequency of use