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Lycopene is most effective when utilized as one strategic piece of a comprehensive, holistic management plan that includes aggressive pacing, nervous system regulation, adequate hydration, and careful symptom tracking

The pH overlap is narrow but functional

Studies indicate that it can inactivate the tyrosinase enzyme and quench free radicals that contribute to tyrosinase and melanin formation, thereby serving as a skin-lightening or de- pigmenting agent

When the fibrous striations are fully formed and elliptical, meaning that melanin synthesis has begun, enzymes such as TRP-1, TYR, and dopachrome tautomerase (DCT) are required to synthesise the phenolic amino acid precursor L-tyrosine into melanin [184]

TB-500 has been evaluated in laboratory models studying cellular migration, muscle regeneration, and wound healing