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The available findings suggest that silymarin: Can positively influence LDL and VLDL cholesterol levels Significantly increased HDL cholesterol (the so-called "good cholesterol") in studies Can improve oxidative status in the bloodstream Can counteract the reduction of glutathione in the liver caused by a high-cholesterol diet These findings come from clinical studies that were, however, in some cases methodologically heterogeneous

Figure 4 2.3.4 The gut microbiome in ALS pathogenesis Recent studies have shown that the gut microbiome, the community of bacteria living in our digestive system may play an important role in the development and progression of ALS

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