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Innovent's mazdutide has gone further: China's NMPA approved mazdutidethe world's first dual GCG [glucagon receptor]/GLP-1 receptor agonistfor chronic weight management in June 2025
These results highlight the potential of oral GLP1 options to expand patient access and accelerate adoption within the market
However, the timeline varies significantly depending on starting dose, dose escalation speed, and individual tolerance
Recent phase 3 research involving oral semaglutide in early Alzheimers disease has also reinforced the need for caution: promising biology does not always translate into meaningful clinical benefit
The UK recommendation is 30g per day, but most adults already fall short
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