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Isoform-specific binding of selenoprotein P to the -propeller domain of apolipoprotein E receptor 2 mediates selenium supply
In addition, antioxidants that protect the liver from ROS damage and lipid peroxidation may be depleted: GSH, vitamin E, vitamin C and beta-carotene were found to be reduced in the NASH setting (38, 39)
Zheng, P
Trace amounts can form during production but the EU's Scientific Committee on Consumer Safety has concluded that levels at/below 10 ppm in finished products are safe (commercial products consistently fall within acceptable margins)
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