As the body's primary endogenous antioxidant, it plays a critical role in neutralizing free radicals, regenerating other antioxidants like vitamins C and E, and maintaining cellular health and longevity 1-4
is also funded by NIH R01AI172112, NIH P01 HL136275, and UVA SIF Immunology, Imaging and Informatics for Precision Immunomedicine in CVD
Robb, G
NAC and Oxidative Stress Oxidative stress results when an imbalance occurs and our cells produce too many free radicals, knocking oxidants and antioxidants out of balance
Solid lipid nanoparticles These delivery systems have potential due to their many advantages, such as their non-toxic payloads, improved patient compliance, increased drug stability, enhanced absorption, an elimination half-life prolonged by the high drug load determined by the particular drug, increased drug incorporation into nanoparticles due to the biophysical properties of the drug, improved cellular delivery, a controlled release mechanism, and the ability to produce multiple drug-particle combinations [39]