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Medical organizations including the American College of Obstetricians and Gynecologists acknowledge that some GLP-1 drugs may be compatible with lactation on a case-by-case basis, but semaglutide specifically lacks sufficient human data for confident reassurance
Liu P, Wu D, Duan J, Xiao H, Zhou Y, Zhao L, et al
Oral GLP-1 therapies are viewed as a major future growth segment because they can improve access and reduce injection-related barriers
The molecule is based on a GIP skeleton with amino acid modifications and C20 acylation, has a mass of approximately 4731 g/mol, and its long half-life (albumin binding) forms the basis of the weekly regimen in the clinical program
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