One of the things where for me, the rubber really met the road with this was its one thing to talk about weight, health and to talk about the weight, health, hormones, and its another to be able to actually evaluate their function, and because they only stay on for 2 to 5 minutes, I was talking to a bunch of individuals about the research and they were like, you know, actually the research is really hard because we cant show whats happening to your own hormones
The primary mechanisms of action include: Enhancing insulin secretion from pancreatic beta cells in a glucose-dependent manner, meaning insulin is only released when blood glucose levels are elevated Suppressing glucagon release from pancreatic alpha cells, which reduces hepatic glucose production Slowing gastric emptying , which helps moderate post-meal blood glucose spikes Reducing appetite through central nervous system effects, leading to decreased caloric intake and weight loss Examples of GLP-1 receptor agonists available in the UK include exenatide (Byetta, Bydureon), liraglutide (Victoza for diabetes, Saxenda for weight management), dulaglutide (Trulicity), lixisenatide (Lyxumia), and semaglutide (Ozempic/Rybelsus for diabetes, Wegovy for weight management)
Taniya De Silva, an endocrinologist at LSU Health New Orleans who frequently treats patients with diabetes and obesity
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