Neither has passed the phase 2-3 stages required for marketing authorization
V., Samaddar, M., Sinha, D., Purushotham, J
Increasing evidence from clinical and animal studies suggest that hair greying is an independent predictor of serious dermatological pathologies and other conditions [200], such as vitiligo [133], cardiovascular diseases[41], oculocutaneous albinism [197], and osteoporosis[167]
Unlike vitamins or herbal compounds, Epitalon: Acts at a cellular signalling level Influences gene expression related to aging Has systemic effects beyond symptom relief Because of its mechanism of action, Epitalon is classified as a medical longevity therapy , not an over-the-counter wellness product
Pickart estimated lethal dose at approximately 22,500 mg for humans (300-fold above effective doses), with animal LD50 studies in mice showing 8 mg per 25g mouse (320 mg/kg, translating to ~22,400 mg for 154 lb human)