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There were 69 subjects in the placebo group and 62 in the hydrolyzed collagen group

Breaks make sense for users experiencing treatment plateau where benefits cease increasing despite continued application suggesting diminishing returns from ongoing use, comfortable with some benefit decline during off periods accepting fluctuation in skin quality, budget-conscious seeking to minimize annual treatment costs through intermittent purchasing, philosophically preferring avoiding indefinite dependency on any skincare product, planning life changes incompatible with consistent application (extended travel, relocation, financial shifts), and wanting to assess whether improvements prove durable or require continuous maintenance before committing to indefinite treatment

Yu T, Guo J, Zhu S et al (2020) Protective effects of selenium-enriched peptides from Cardamine violifolia on d-galactose-induced brain aging by alleviating oxidative stress, neuroinflammation, and neuron apoptosis

Shed is the best overall choice if you want fast, affordable access to compounded semaglutide or tirzepatide, as well as brand-name options like Wegovy and Zepbound

Using partially degraded peptide produces unpredictable results because you can't visually assess potency loss