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For example, new drugs could be approved that interact with Repatha

Additionally, these agents slow gastric emptying, which prolongs the sensation of fullness after meals and reduces appetite through effects on brain centres that regulate hunger

When tirzepatides extra makes clinical sense: Severe obesity with stacked risks (BMI over 30, diabetes, hypertension, MASLD, sleep apnea, etc.) High orthopedic burden (advanced knee or hip arthritis, foot/ankle issues) Presurgical timelines (preparing for bariatric, orthopedic, or heart surgeries) When semaglutide may be the better fit: Mild to moderate obesity with lower shortterm risk

Borgonje PE et al

The impact of GLP-1s gaining more cultural consciousness is far reaching: a staggering 67% of Americans would even prefer to stay in a job they dislike to maintain access to coverage for these medications