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A message is only useful if the cell has the energy to act on it, which is why fueling the system with NAD+ and then directing specific work with a peptide can be a logical pairing

Initially investigated for its potential to treat neurodegenerative diseases like Alzheimers and Parkinsons, this small synthetic peptide is known to bind with high affinity to hepatocyte growth factor (HGF) and its receptor c-Met, thereby promoting neuronal differentiation, dendritic branching, and synaptic plasticity

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Colloids Surf B Biointerfaces 209(Pt 1):112155

Intrinsic factor is a mucoprotein enzyme produced by the parietal cells of the stomach (which also make hydrochloric acid)