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Retatrutide mimics three hormones (GLP-1, GIP and glucagon), whereas Mounjaro mimics two (GLP-1 and GIP)
Without insurance, these drugs, at the doses used to reduce obesity, run to $1,000/month out of pocket
The reduction in adiposity may help protect muscle tissue from muscle wasting, which is often seen in obesity-associated catabolic states [28], in addition, sustained negative energy balance promotes fat loss, but also contributes to lean tissue catabolism
excess is renally excreted, though very high levels can cause dermatologic or metabolic effects
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