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In BV2 microglial cells, EtOH exposure (25100 mM) increases expression of P2X4 and P2X7 receptors [41]both key mediators of Ca influx and glial activation
& Xu, J
63 Considering that T2DM and MASLD can reciprocally cause and affect each other, and given liraglutides potential therapeutic characteristics for MASLD, which may be beneficial for anti-fibrosis, more aggressive use of higher doses may bring greater clinical benefits in some groups, such as those with higher-grade fibrosis with or without T2DM
This effect was observed without any impact on the marker expression of Lgr5 + stem cells, goblet cells, and Paneth cells
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