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GSH augmentation deserves investigation as a beneficial therapeutic approach for not only PD but also numerous other CNS disorders for which GSH deficiency and GSH-related enzyme deficits have been documented (multiple sclerosis, 25,26 autism, 2729 Alzheimers disease, 30,31 schizophrenia, 32,33 and bipolar disease 34 )

Compounded medications have not been approved by the FDA for safety, effectiveness, or quality and should only be used when FDA-approved medications are unavailable

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Table 1 Overview of cell death types

Asher believes vocal fold nodules and polyps are actually a tissue response to chronic and uncontrolled oxidative stress