During the item generation and discussion and clarification phases, the experts identified 14 distinct challenges: costs, supply challenges, lack of evidence, polypharmacy, barriers to prescription, lack of knowledge, adherence concerns, aversion to injection therapy, clinical inertia, titration needs, perceived health state, fear of adverse effects, lack of clinical guideline recommendations, and lack of measurable outcomes to guide therapy
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Gradual titration was used to reduce gastrointestinal adverse effects common to incretin therapies
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Los GLP-1 y prdida de peso: qu nos dice la evidencia Aunque se desarrollaron originalmente para diabetes tipo 2, los agonistas del GLP-1 han demostrado un impacto significativo en la reduccin de peso corporal
