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Wang, Fibroblasts and myofibroblasts in wound healing: force generation and measurement
Operates at the nuclear protein-interaction level: Unlike metabolic or hormonal peptides that act on membrane receptors, FOXO4-DRI functions by disrupting nuclear protein interactions
Overall, flavonoids act on multiple pathogenic targetsoxidative stress, inflammation, mitochondrial dysfunction, and protein aggregationto confer neuroprotection, supporting epidemiological observations that flavonoid-rich diets may help prevent or slow the progression of PD
Ultimately, open and informed dialogue between patients and their healthcare team remains the cornerstone of safe prescribing
