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Ultimately, this FOXO4-DRI-mediated mechanism selectively eliminates senescent endothelial cells, which in turn attenuates vascular inflammation and improves endothelial-dependent vasodilation, conferring a significant protective effect on vascular function

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Benefits Exceptional weight loss: Patients with obesity (without diabetes) lost an average of 2224% of body weight at 48 weeks on 812 mg doses [3] [4]

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