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However, the use of these medications is controversial because they are not approved by the U.S
A central finding is that gradual dose escalation measurably reduces the frequency and severity of these events
Knowing ahead of time who is likely to respond would help patients get on the right drugs faster a step toward precision medicine, Gloyn said
It may be preferred for those who have fewer complicating health factors or for individuals responding well to GLP-1 alone
- In SURMOUNT-2, people taking Zepbound at the 15 mg dose experienced average weight reductions of 15.7% (34.4 pounds) and people taking Zepbound at the 10 mg dose experienced average weight reductions of 13.4% (29.8 pounds) compared to placebo 3.3% (7.0 pounds)
