For US patients, the combination of transparent pricing, a licensed contracted pharmacy department, and a clear referral process makes the decision straightforward
Patients in these two states are not eligible for Direct Meds' GLP-1 programs regardless of clinical eligibility
In November 2023, the FDA granted approval for Zepbound (tirzepatide) for chronic weight management in adults with obesity (body mass index 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbid condition such as hypertension, dyslipidemia, type 2 diabetes, obstructive sleep apnea, or cardiovascular disease
When compared with nonusers, tirzepatide was linked to a markedly heightened risk of the composite outcome (HR 1.48), whereas other GLP-1 RAs illustrated no clinically meaningful risk increase (HR 1.07)
Why dry mouth shows up on a GLP-1 Cottonmouth is common enough that people assume the drug is drying their saliva, but the usual story is simpler and more fixable: you are mildly dehydrated