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According to the American Diabetes Association, it stimulates insulin secretion from the pancreas and is used to improve glycemic control (blood sugar levels) in people with type- 2 diabetes mellitus
ED can be an early warning sign of cardiovascular disease or diabetes, and NICE recommends proper medical assessment including cardiovascular risk evaluation for all men presenting with erectile dysfunction
Starting both simultaneously may increase early tolerability challenges, which is why staggered introductionbeginning one medication, allowing adjustment, then adding the secondoften proves more practical
These modifications extend their half-lives from hours to days, allowing once-daily or once-weekly dosing
PLoS ONE 9 , e94140 (2014)
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