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Current approaches include: Continuous Use Approach: Based on clinical trials that used continuous daily administration for 12-24 weeks without scheduled breaks

In a phase IIa, randomized, open-label study with an active comparator, efinopegdutide was compared with semaglutide over 24 weeks in individuals with elevated liver fat content (LFC)

PlexusDx precision-wellness approach examines genetic predispositions in weight-regulation pathways to help providers and patients contextualize treatment choices within a more personalized framework, rather than defaulting to trial-and-error medication selection

Most people notice increased appetite suppression within one to two weeks of the switch, sometimes with a temporary increase in GI side effects as the body adjusts to the dual agonist

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