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miR-1246, released via exosomes from CRC cells, can reprogram tumor-associated macrophages (TAMs) toward a pro-tumor phenotype by altering their metabolic state, thereby supporting CRC growth and immune evasion [115]
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[71] A separate trial in women undergoing in vitro fertilization found that oral SOD supplementation increased serum catalase activity over 12 weeks compared to baseline, suggesting improvement in antioxidant defense
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207 With the assistance of inhibitory and activating receptors on the cell surface such as LAF-1 and VLA-4, they could efficient target specific cells, providing the potential of brain-targeted delivery
