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Since 90% of the bodys serotonin originates in the gut, modulating enteric serotonin production could influence central serotonergic tone through vagal afferents that relay gut signals to brain serotonin-producing raphe nuclei
Numbness or tingling sensations Pain in the hands and feet Weakness or fatigue Risk Factors for Developing B12 Deficiency Neuropathy Some people are more likely to get nerve damage from B12 shortage
However, these mild local and site reactions are generally harmless and resolve independently without any intervention
So we need to care about all of it and we need to just not make excuses and also not rely on one solution or another and just go after it
The two are structurally unrelated and act through different biological pathways, which is the main reason researchers became interested in studying them in combination
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