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High doses of 3000 g per daily dose
Intended Setting: Laboratory research use only
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During the enzymatic process leading to the dissociation of H 2 O 2 , catalase is first oxidised to a hypervalent iron intermediate known as compound I and then reduced back to its resting state by a second H 2 O 2 molecule
In CKD, reduced renal function limits TMAO clearance, whereas excessive levels in metabolic syndrome increase the risk of T2D and cardiovascular diseases
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