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Transdermal delivery, favoured for its active and passive approaches and advantages over topical delivery, has been extensively studied and employed for therapeutics

In contrast to the results of some previous studies, our participants with insomnia included fewer alcohol drinkers compared to participants without insomnia

Side effects are rare but may include mild redness or irritation at the injection site

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184 demonstrated that GR24 application upregulated the expression of several SL biosynthetic genes ( PbD27, PbDAD1, PbCYP711 ) and signaling components ( PbD14, PbMAX2A, PbPDR1 ), further supporting the involvement of MAX2 in SL mediated stress responses