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Medication Adjustments and Ancillary Symptom Support If dietary modifications and dose adjustment don't resolve nausea within 34 weeks, providers may recommend anti-nausea medication

NNMT is an enzyme involved in nicotinamide metabolism and energy-related pathways

The cascade of intracellular reactions triggered as a result leads to a decrease in the production of hunger-stimulating neuropeptides (specifically, neuropeptide Y) and, as a result, a relatively higher level of neuropeptides stimulating satiety

The NST, in turn, signals to a number of other brain centres that impact satiety

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