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Its entry follows the launch of Wegovy, another semaglutide-based drug, in June 2025, intensifying competition in the GLP-1 receptor agonist segment

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Critical evaluation Strengths - Addresses unmet need for disease modifying diabetes therapies, also applicable to related metabolic diseases - Combines regenerative potential with metabolic control - Supported by robust preclinical models and biomarker endpoints Limitations - Translational challenges in moving from preclinical models to human cells regeneration - Long term safety must be carefully evaluated, given its role in gastric physiology - Regulatory guidelines for such therapies are still evolving