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PPADS also partially blocked GLUTag cell responses to exogenously applied ATP (38 15% block, n = 47) and had inconsistent effects on the satellite-glial cells that responded to CNO application (Supplementary Figure 4)
Use this checkpoint as a conversation starter with your healthcare provider, not as a reason to give up
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If you need to be outside for extended periods, take breaks to warm up indoors whenever possible
If significant deficiency is confirmed via blood test, a loading dose protocol may be recommended in line with NICE guidance typically more frequent injections over the initial weeks to rapidly restore levels
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