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Epilepsy Res (1988) 2:8795.10.1016/0920-1211(88)90024-1 65 KristensenASJenkinsMABankeTGSchousboeAMakinoYJohnsonRCet alMechanism of Ca 2+ /calmodulin-dependent kinase II regulation of AMPA receptor gating

Nausea Vomiting Constipation Diarrhea Acid reflux Bloating Reduced appetite Stomach discomfort Most side effects improve gradually after the body adapts to treatment

RCTs have previously been successful in influencing management and public health policy, with examples in the Diabetes Prevention Programme [21], DiRECT [22] and DROPLET [23] trials

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