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La severidad es generalmente leve a moderada, pero en algunos casos puede ser lo suficientemente significativa como para requerir reduccin de dosis o discontinuacin
The compound enters circulation directly, rather than waiting on digestion
It is widely recognised that metformin improves glycaemic control with a good safety profile, weight neutrality or weight loss, lack of associated hypoglycaemia, reduced cardiovascular mortality and low cost [3]
Researchers sought volunteers who were interested in reducing their drinking
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