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However, these beneficial effects were attenuated by inhibiting SIRT1 expression
The TGA recommends that semaglutide supplies be reserved for those who have no other treatment options available to them
But there can be also more severe side effects, such as damage to the pancreas, eyes, gallbladder and kidneys, as well as dangerously low blood sugar levels, acid reflux and hair loss
Diarrhea is less common but can occur, especially at higher doses
This is called spectrum bias in which the sensitivity and specificity of a particular cut point is dependent on prevalence
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