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10.1016/0166-3542(95)00008-A Antiviral Res
Given its essential role in the detoxification of lipid hydroperoxides, and its overexpression in most of myeloid malignancies, GPX4 inhibition has emerged as a promising therapeutic strategy to specifically trigger ferroptosis and eradicate myeloid leukemia cells
The IGF-1R, which is ubiquitously expressed across nearly all cell types in the organism, consists of two and two subunits linked by disulfide bonds (Bailes and Soloviev, 2021)
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