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10.1053/j.gastro.2007.03.054 Gastroenterology 10 BaggioL
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More importantly, endocrinologists should work coordinately with cardiologists and pharmacologists to establish GLP-1RA-dependent and independent effects in preparation for precisely commencing therapy with GLP-1RAs in suitable targeted patient categories
Preclinical studies in rodents have shown an association between GLP-1 receptor activation and thyroid C-cell changes, although a direct causal link in humans has not been established, and UK/EU SmPCs for authorised GLP-1 RAs do not list MTC or MEN2 as a formal contraindication
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