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Accordingly, under the law, marijuana is any cannabis plant that contains 0.3 percent or more of THC, and hemp is defined as the cannabis plant that contains less than 0.3 percent of THC

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Monitoring: Metabolic: Monitor for signs/symptoms of hypoglycemia GI: Monitor for signs/symptoms of pancreatitis after starting therapy Renal: Monitor renal function in patients with renal dysfunction reporting severe adverse GI reactions (especially when starting or escalating doses) Patient advice: Read the US FDA-approved patient labeling (Medication Guide and Instructions for Use)

This leads to the cleavage and translocation of AIF from the mitochondrial intermembrane space to the nucleus, phosphorylation of the histone H2A family member H2AX, mitochondrial release of the death-inducing protein Smac/direct IAP-binding protein with low PI (DIABLO), and inhibition of the anti-apoptotic protein X-linked inhibitor of apoptosis (XIAP)

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